Residual Activatability of Circulating Tfh17 Predicts Humoral Response to Thymodependent Antigens in Patients on Therapeutic Immunosuppression

The generation of antibodies against protein antigens (such as donor-specific HLA molecules) requires that T follicular helper cells (Tfh) provide help to B cells. Immunosuppressive (IS) armamentarium prevents T cell activation, yet a significant proportion of renal transplant patients develop donor...

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Detalles Bibliográficos
Autores principales: Dahdal, Suzan, Saison, Carole, Valette, Martine, Bachy, Emmanuel, Pallet, Nicolas, Lina, Bruno, Koenig, Alice, Monneret, Guillaume, Defrance, Thierry, Morelon, Emmanuel, Thaunat, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370621/
https://www.ncbi.nlm.nih.gov/pubmed/30804950
http://dx.doi.org/10.3389/fimmu.2018.03178

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