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Dietary Omega-3 Polyunsaturated Fatty Acid Deprivation Does Not Alter Seizure Thresholds but May Prevent the Anti-seizure Effects of Injected Docosahexaenoic Acid in Rats

Background: Brain concentrations of omega-3 docosahexaenoic acid (DHA, 22:6n-3) have been reported to positively correlate with seizure thresholds in rodent seizure models. It is not known whether brain DHA depletion, achieved by chronic dietary omega-3 polyunsaturated fatty acid (PUFA) deficiency,...

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Detalles Bibliográficos
Autores principales:	Taha, Ameer Y., Trepanier, Marc-Olivier, Coibanu, Flaviu A., Saxena, Anjali, Jeffrey, Melanie A., Taha, Nadeen M. Y., Burnham, W. McIntyre, Bazinet, Richard P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370649/ https://www.ncbi.nlm.nih.gov/pubmed/30804888 http://dx.doi.org/10.3389/fneur.2018.01188

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