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Early Stage Alpha-Synuclein Amyloid Fibrils are Reservoirs of Membrane-Binding Species
The presence of αSN fibrils indisputably associates with the development of synucleinopathies. However, while certain fibril morphologies have been linked to downstream pathological phenotypes, others appear less harmful, leading to the concept of fibril strains, originally described in relation to...
Autores principales: | Skamris, Thomas, Marasini, Carlotta, Madsen, Kenneth L., Foderà, Vito, Vestergaard, Bente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370759/ https://www.ncbi.nlm.nih.gov/pubmed/30741994 http://dx.doi.org/10.1038/s41598-018-38271-2 |
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