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IL1RL1 is dynamically expressed on Cbfb-MYH11(+) leukemia stem cells and promotes cell survival

Acute myeloid leukemia (AML) is often characterized by the presence of specific, recurrent chromosomal abnormalities. One of the most common aberrations, inversion of chromosome 16 [inv(16)], generates the fusion oncogene CBFB-MYH11. Previously, we used a mouse knock-in model to show that Cbfb-MYH11...

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Detalles Bibliográficos
Autores principales: Wang, Yiqian, Richter, Lisa, Becker, Michelle, Amador, Catalina, Hyde, R. Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370767/
https://www.ncbi.nlm.nih.gov/pubmed/30742053
http://dx.doi.org/10.1038/s41598-018-38408-3

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