Cargando…

Changes in tinnitus after vestibular schwannoma surgery

We designed a prospective study to evaluate changes in tinnitus after vestibular schwannoma (VS) surgery. Subjects included 41 patients who were diagnosed with a VS and underwent translabyrinthine microsurgery (TLM) between January 2015 and May 2016. All patients underwent related examinations and w...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jing-Jing, Feng, Yan-Mei, Wang, Hui, Wu, Ya-Qin, Shi, Hai-Bo, Chen, Zheng-Nong, Yin, Shan-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370768/
https://www.ncbi.nlm.nih.gov/pubmed/30742012
http://dx.doi.org/10.1038/s41598-019-38582-y
_version_ 1783394419127353344
author Wang, Jing-Jing
Feng, Yan-Mei
Wang, Hui
Wu, Ya-Qin
Shi, Hai-Bo
Chen, Zheng-Nong
Yin, Shan-Kai
author_facet Wang, Jing-Jing
Feng, Yan-Mei
Wang, Hui
Wu, Ya-Qin
Shi, Hai-Bo
Chen, Zheng-Nong
Yin, Shan-Kai
author_sort Wang, Jing-Jing
collection PubMed
description We designed a prospective study to evaluate changes in tinnitus after vestibular schwannoma (VS) surgery. Subjects included 41 patients who were diagnosed with a VS and underwent translabyrinthine microsurgery (TLM) between January 2015 and May 2016. All patients underwent related examinations and were asked to answer the Tinnitus Handicap Inventory (THI) scale and a visual analog scale (VAS) of tinnitus severity both pre- and postoperatively. Of the 41 patients, 31 (75.6%) suffered from tinnitus before surgery. Microsurgery was associated with an overall decrease in tinnitus (p < 0.001). There was a significant improvement in THI and VAS scores after surgery (p = 0.001 and p = 0.005, respectively). The decrease in THI scores in the low-frequency group was significantly larger than that of the mid- and high-frequency groups after surgery (p = 0.034 and p = 0.001, respectively). The loudness of tinnitus decreased significantly after surgery (p = 0.031). Tinnitus in patients with VS improved after TLM. Patients with mid-/high-frequency tinnitus and louder tinnitus preoperatively seemed to have a worse prognosis than those with low-frequency and quieter tinnitus.
format Online
Article
Text
id pubmed-6370768
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-63707682019-02-15 Changes in tinnitus after vestibular schwannoma surgery Wang, Jing-Jing Feng, Yan-Mei Wang, Hui Wu, Ya-Qin Shi, Hai-Bo Chen, Zheng-Nong Yin, Shan-Kai Sci Rep Article We designed a prospective study to evaluate changes in tinnitus after vestibular schwannoma (VS) surgery. Subjects included 41 patients who were diagnosed with a VS and underwent translabyrinthine microsurgery (TLM) between January 2015 and May 2016. All patients underwent related examinations and were asked to answer the Tinnitus Handicap Inventory (THI) scale and a visual analog scale (VAS) of tinnitus severity both pre- and postoperatively. Of the 41 patients, 31 (75.6%) suffered from tinnitus before surgery. Microsurgery was associated with an overall decrease in tinnitus (p < 0.001). There was a significant improvement in THI and VAS scores after surgery (p = 0.001 and p = 0.005, respectively). The decrease in THI scores in the low-frequency group was significantly larger than that of the mid- and high-frequency groups after surgery (p = 0.034 and p = 0.001, respectively). The loudness of tinnitus decreased significantly after surgery (p = 0.031). Tinnitus in patients with VS improved after TLM. Patients with mid-/high-frequency tinnitus and louder tinnitus preoperatively seemed to have a worse prognosis than those with low-frequency and quieter tinnitus. Nature Publishing Group UK 2019-02-11 /pmc/articles/PMC6370768/ /pubmed/30742012 http://dx.doi.org/10.1038/s41598-019-38582-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wang, Jing-Jing
Feng, Yan-Mei
Wang, Hui
Wu, Ya-Qin
Shi, Hai-Bo
Chen, Zheng-Nong
Yin, Shan-Kai
Changes in tinnitus after vestibular schwannoma surgery
title Changes in tinnitus after vestibular schwannoma surgery
title_full Changes in tinnitus after vestibular schwannoma surgery
title_fullStr Changes in tinnitus after vestibular schwannoma surgery
title_full_unstemmed Changes in tinnitus after vestibular schwannoma surgery
title_short Changes in tinnitus after vestibular schwannoma surgery
title_sort changes in tinnitus after vestibular schwannoma surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370768/
https://www.ncbi.nlm.nih.gov/pubmed/30742012
http://dx.doi.org/10.1038/s41598-019-38582-y
work_keys_str_mv AT wangjingjing changesintinnitusaftervestibularschwannomasurgery
AT fengyanmei changesintinnitusaftervestibularschwannomasurgery
AT wanghui changesintinnitusaftervestibularschwannomasurgery
AT wuyaqin changesintinnitusaftervestibularschwannomasurgery
AT shihaibo changesintinnitusaftervestibularschwannomasurgery
AT chenzhengnong changesintinnitusaftervestibularschwannomasurgery
AT yinshankai changesintinnitusaftervestibularschwannomasurgery