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Flavones hydroxylated at 5, 7, 3′ and 4′ ameliorate skin fibrosis via inhibiting activin receptor-like kinase 5 kinase activity

Skin fibrosis is mainly characterized by excessive collagen deposition. Studies have recently identified a number of flavonoids with variable structures that have the potency of inhibiting collagen synthesis and thus attenuating organ fibrosis. In this study, we found that flavones with 5, 7, 3′, 4′...

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Detalles Bibliográficos
Autores principales:	Zhang, Yifan, Wang, Jing, Zhou, Sizheng, Xie, Zhibo, Wang, Chuandong, Gao, Ya, Zhou, Jia, Zhang, Xiaoling, Li, Qingfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370799/ https://www.ncbi.nlm.nih.gov/pubmed/30741930 http://dx.doi.org/10.1038/s41419-019-1333-7

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