Cargando…
Obesity-associated inflammation triggers an autophagy–lysosomal response in adipocytes and causes degradation of perilipin 1
In obesity, adipocytes exhibit high metabolic activity accompanied by an increase in lipid mobilization. Recent findings indicate that autophagy plays an important role in metabolic homeostasis. However, the role of this process in adipocytes remains controversial. Therefore, we performed an overall...
Autores principales: | Ju, Liping, Han, Junfeng, Zhang, Xiaoyan, Deng, Yujie, Yan, Han, Wang, Congrong, Li, Xiaohua, Chen, Shuqin, Alimujiang, Miriayi, Li, Xu, Fang, Qichen, Yang, Ying, Jia, Weiping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370809/ https://www.ncbi.nlm.nih.gov/pubmed/30741926 http://dx.doi.org/10.1038/s41419-019-1393-8 |
Ejemplares similares
-
Enhanced expression of Survivin has distinct roles in adipocyte homeostasis
por: Ju, Liping, et al.
Publicado: (2017) -
Bola3 Regulates Beige Adipocyte Thermogenesis via Maintaining Mitochondrial Homeostasis and Lipolysis
por: Bai, Ningning, et al.
Publicado: (2021) -
PARP12 is required for mitochondrial function maintenance in thermogenic adipocytes
por: Hu, Fan, et al.
Publicado: (2022) -
Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation
por: Takahashi, Yu, et al.
Publicado: (2016) -
Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes
por: Mizunoe, Yuhei, et al.
Publicado: (2020)