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High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia
Decreased nitric oxide (NO) bioavailability plays a critical role in the pathophysiology of preeclampsia (PE). Recent evidence indicates that S-glutathionylation may occur on the endothelial nitric oxide synthase (eNOS), leading to eNOS uncoupling, characterized by a decreased NO production and an i...
Autores principales: | Guerby, Paul, Swiader, Audrey, Augé, Nathalie, Parant, Olivier, Vayssière, Christophe, Uchida, Koji, Salvayre, Robert, Negre-Salvayre, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370867/ https://www.ncbi.nlm.nih.gov/pubmed/30738311 http://dx.doi.org/10.1016/j.redox.2019.101126 |
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