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Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells()
Dysfunctional inflammatory pathways are associated with an increased risk of cancer, including colorectal cancer. We have previously identified and enriched for a self-renewing, colon cancer stem cell (CCSC) subpopulation in primary sporadic colorectal cancers (CRC) and a related subpopulation in ul...
Autores principales: | Fisher, Robert C., Bellamkonda, Kishan, Alex Molina, L., Xiang, Shao, Liska, David, Sarvestani, Samaneh K., Chakrabarti, Susmita, Berg, Annamarie, Jorgensen, Marda L., Hatala, Denise, Chen, Sugong, Aiello, Alexandra, Appelman, Henry D., Scott, Edward W., Huang, Emina H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370871/ https://www.ncbi.nlm.nih.gov/pubmed/30738331 http://dx.doi.org/10.1016/j.neo.2018.12.007 |
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