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TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3

TRADD is an adaptor for TNFR1-induced apoptosis and NFκB activation. However, TRADD-deficient mice undergo normal development and contain normal lymphoid populations, which contrasts with an embryonic defect in mice lacking FADD, the shared adaptor mediating apoptosis. Recent studies indicate FADD s...

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Detalles Bibliográficos
Autores principales:	Dowling, John P., Alsabbagh, Mohamed, Del Casale, Christina, Liu, Zheng-Gang, Zhang, Jianke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370879/ https://www.ncbi.nlm.nih.gov/pubmed/30741936 http://dx.doi.org/10.1038/s41467-019-08584-5

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