Cargando…

The Ethanolic Extract of Caesalpinia sappan Heartwood Inhibits Cerebral Ischemia/Reperfusion Injury in a Rat Model Through a Multi-Targeted Pharmacological Mechanism

Background: Caesalpinia sappan L. (C. sappan) is a traditional Chinese medicinal plant. The dried heartwood of C. sappan (also known as Sappan wood) has been widely used for the folkloric medical treatment of ischemic cerebral stroke in China. However, the detailed underlying pharmacological mechani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wan, Yan-Jun, Xu, Li, Song, Wen-Ting, Liu, Yu-Qi, Wang, Li-Chao, Zhao, Ming-Bo, Jiang, Yong, Liu, Lian-Ying, Zeng, Ke-Wu, Tu, Peng-Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370896/ https://www.ncbi.nlm.nih.gov/pubmed/30804781 http://dx.doi.org/10.3389/fphar.2019.00029

Ejemplares similares

Pharmacognostical Evaluation of Caesalpinia sappan Heartwood
por: Badami, Shrishailappa, et al.
Publicado: (2003)

Two New Phenolic Compounds from the Heartwood of Caesalpinia sappan L.
por: Zhao, Ming-Bo, et al.
Publicado: (2013)

Development of Intelligent Gelatin Films Incorporated with Sappan (Caesalpinia sappan L.) Heartwood Extract
por: Romruen, Orapan, et al.
Publicado: (2022)

Protective Effects of Caesalpinia sappan Linn. and Its Bioactive Compounds on Cardiovascular Organs
por: Syamsunarno, Mas Rizky AA, et al.
Publicado: (2021)

A New 3-Benzylchroman Derivative from Sappan Lignum (Caesalpinia sappan)
por: Fu, Lin-chun, et al.
Publicado: (2008)

In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
por: Naik Bukke, Arunkumar, et al.
Publicado: (2018)

New Cassane Diterpenoids from Caesalpinia sappan and Their Antiplasmodial Activity
por: Zhu, Nai-Liang, et al.
Publicado: (2017)

Optimization of choline chloride-glycerol based natural deep eutectic solvent for extraction bioactive substances from Cinnamomum burmannii barks and Caesalpinia sappan heartwoods
por: Sakti, Aditya Sindu, et al.
Publicado: (2019)

Melanogenesis Inhibition by Homoisoflavavone Sappanone A from Caesalpinia sappan
por: Chang, Te-Sheng, et al.
Publicado: (2012)

A Comprehensive Review on Bioactive Compounds Found in Caesalpinia sappan
por: Vij, Twinkle, et al.
Publicado: (2023)

Activity Screening of the Herb Caesalpinia sappan and an Analysis of Its Antitumor Effects
por: Li, Yuan, et al.
Publicado: (2021)

Effect of Ethanolic Caesalpinia sappan Fraction on In Vitro Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus
por: Arjin, Chaiwat, et al.
Publicado: (2021)

Complete plastome sequence of Caesalpinia sappan Linnaeus, a dyestuff and medicinal species
por: Li, Lin-Ming, et al.
Publicado: (2020)

Cytotoxic and Pro-Apoptotic Effects of Cassane Diterpenoids from the Seeds of Caesalpinia sappan in Cancer Cells
por: Bao, Han, et al.
Publicado: (2016)

PASS-Predicted Hepatoprotective Activity of Caesalpinia sappan in Thioacetamide-Induced Liver Fibrosis in Rats
por: Kadir, Farkaad A., et al.
Publicado: (2014)

Methanol extract from Vietnamese Caesalpinia sappan induces apoptosis in HeLa cells
por: Hung, Tran Manh, et al.
Publicado: (2014)

Moisturized and non-irritating hand gel based on sappan wood (Caesalpinia sappan l.) and limau citrus peel (Citrus amblycarpa (hassk.) ochse) extracts
por: Sari, Dina Yuspita, et al.
Publicado: (2023)

Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets
por: Chang, Yi, et al.
Publicado: (2013)

Retracted: PASS-Predicted Hepatoprotective Activity of Caesalpinia sappan in Thioacetamide-Induced Liver Fibrosis in Rats
por: The Scientific World Journal,
Publicado: (2018)

Antidiabetic activity and acute toxicity of combined extract of Andrographis paniculata, Syzygium cumini, and Caesalpinia sappan
por: Masaenah, Eem, et al.
Publicado: (2021)

Network Pharmacology Study to Reveal the Potentiality of a Methanol Extract of Caesalpinia sappan L. Wood against Type-2 Diabetes Mellitus
por: Adnan, Md., et al.
Publicado: (2022)

Hypoglycemic Effect of a Combined Andrographis paniculata and Caesalpinia sappan Extract in Streptozocin-Induced Diabetic Rats
por: Wediasari, Febrika, et al.
Publicado: (2020)

Anticancer activity of Caesalpinia sappan by downregulating mitochondrial genes in A549 lung cancer cell line
por: Widodo, Nashi, et al.
Publicado: (2022)

Exploring the Potential of Roselle Calyx and Sappan Heartwood Extracts as Natural Colorants in Poly(butylene Succinate) for Biodegradable Packaging Films
por: Nansu, Wordpools, et al.
Publicado: (2023)

One-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death
por: Uddin, Golam Mezbah, et al.
Publicado: (2015)

Simultaneous determination of brazilin and protosappanin B in Caesalpinia sappan by ionic-liquid dispersive liquid-phase microextraction method combined with HPLC
por: Xia, Zhaoyang, et al.
Publicado: (2017)

Metabolomics profiling to characterize cerebral ischemia-reperfusion injury in mice
por: Chen, Qiong, et al.
Publicado: (2023)

Network Pharmacology Reveals the Mechanism of Activity of Tongqiao Huoxue Decoction Extract Against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia-Reperfusion Injury
por: Wu, Si-peng, et al.
Publicado: (2021)

Spectrum effect correlation of yangyin tongnao granules on cerebral ischemia-reperfusion injury rats
por: Zhang, Yangyang, et al.
Publicado: (2022)

Danhong Injection Attenuates Cerebral Ischemia-Reperfusion Injury in Rats Through the Suppression of the Neuroinflammation
por: Du, Haixia, et al.
Publicado: (2021)

Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1
por: Gao, Qing, et al.
Publicado: (2022)

Color and molecular structure alterations of brazilein extracted from Caesalpinia sappan L. under different pH and heating conditions
por: Ngamwonglumlert, Luxsika, et al.
Publicado: (2020)

A Potential of New Untreated Bio-Reinforcement from Caesalpinia sappan L. Wood Fiber for Polybutylene Succinate Composite Film
por: Martwong, Ekkachai, et al.
Publicado: (2022)

The Cytotoxic and Anti-Migratory Properties of Caesalpinia sappan and Ficus septica, in Combination with Doxorubicin on 4T1 TNBC Cells with Nephroprotective Potential
por: Haryanti, Sari, et al.
Publicado: (2022)

Isorhynchophylline Ameliorates Cerebral Ischemia/Reperfusion Injury by Inhibiting CX3CR1-Mediated Microglial Activation and Neuroinflammation
por: Deng, Yuanyuan, et al.
Publicado: (2021)

Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury
por: Mo, Zhizhun, et al.
Publicado: (2022)

Modulation of gut microbiota alleviates cerebral ischemia/reperfusion injury in rats by inhibiting M1 polarization of microglia
por: Li, Hai-Jun, et al.
Publicado: (2023)

SIK2 Improving Mitochondrial Autophagy Restriction Induced by Cerebral Ischemia-Reperfusion in Rats
por: Zhang, Ran, et al.
Publicado: (2022)

Metabolomic Profiling of Brain Protective Effect of Edaravone on Cerebral Ischemia-Reperfusion Injury in Mice
por: Ma, Hui-fen, et al.
Publicado: (2022)

Anti-Myocardial Ischemia Reperfusion Injury Mechanism of Dried Ginger-Aconite Decoction Based on Network Pharmacology
por: Xie, Feng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s4p20m9nfo5n2bbbm3m6s6prqa