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Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism

Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS). We have previously demonstrated that the combination therapy of fingolimod (FTY720) and transplanted neural stem cells (NSCs)...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Lu, Xin-Yu, Ye, Ze-Qin, Ciric, Bogoljub, Ma, Cun-Gen, Rostami, Abdolmohamad, Li, Xing, Zhang, Guang-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371042/
https://www.ncbi.nlm.nih.gov/pubmed/30804753
http://dx.doi.org/10.3389/fncel.2019.00014