Cargando…
p-21 Activated Kinase as a Molecular Target for Chemoprevention in Diabetes †
Hypothesis: Anti-diabetic drugs modulate p-21 activated kinase (PAK) signaling. Introduction: Type 2 diabetes mellitus (T2DM) is a chronic inflammatory disease associated with increased cancer risk. PAK signaling is implicated in cellular homeostasis when regulated, and cancer when unrestrained. Rec...
Autores principales: | Dammann, Kyle, Khare, Vineeta, Coleman, Clyde, Berdel, Henrik, Gasche, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371191/ https://www.ncbi.nlm.nih.gov/pubmed/31011108 http://dx.doi.org/10.3390/geriatrics3040073 |
Ejemplares similares
-
Republished: Tracing PAKs from GI inflammation to cancer
por: Dammann, Kyle, et al.
Publicado: (2014) -
Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1
por: Khare, Vineeta, et al.
Publicado: (2013) -
Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells()
por: Khare, Vineeta, et al.
Publicado: (2014) -
Overexpression of PAK1 Promotes Cell Survival in Inflammatory Bowel Diseases and Colitis-associated Cancer
por: Khare, Vineeta, et al.
Publicado: (2015) -
A Novel PAK1–Notch1 Axis Regulates Crypt Homeostasis in Intestinal Inflammation
por: Frick, Adrian, et al.
Publicado: (2020)