Female genital tract chronic graft-versus-host disease: A narrative review

Graft-versus-host disease is one of the main causes of morbidity and mortality in patients submitted to hematopoietic stem cell transplantation. This study reviewed the prevalence of lower female genital tract graft-versus-host disease following hematopoietic stem cell transplantation. A systematic...

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Detalles Bibliográficos
Autores principales: Machado, Andréa Maria Novaes, Hamerschlak, Nelson, Rodrigues, Morgani, Piccinato, Carla de Azevedo, Podgaec, Sergio, Mauad, Lenira Maria Queiroz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371232/
https://www.ncbi.nlm.nih.gov/pubmed/30793107
http://dx.doi.org/10.1016/j.htct.2018.06.005
Descripción
Sumario:Graft-versus-host disease is one of the main causes of morbidity and mortality in patients submitted to hematopoietic stem cell transplantation. This study reviewed the prevalence of lower female genital tract graft-versus-host disease following hematopoietic stem cell transplantation. A systematic search of the literature for articles published between 1982 and 2015 was performed. A growing number of young women suffering from malignant and benign hematological diseases are receiving allogeneic hematopoietic stem cell transplantation with very satisfactory results in relation to the disease itself. However, these patients face gynecological problems due to graft-versus-host disease. Correct diagnosis and early management are needed to avoid irreversible complications.

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