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Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling
BACKGROUND: Cancer-associated fibroblasts (CAFs), activated by tumour cells, are the predominant type of stromal cells in cancer tissue and play an important role in interacting with neoplastic cells to promote cancer progression. Epithelial-mesenchymal transition (EMT) is a key feature of metastati...
Autores principales: | Goulet, Cassandra Ringuette, Champagne, Audrey, Bernard, Geneviève, Vandal, Dominique, Chabaud, Stéphane, Pouliot, Frédéric, Bolduc, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371428/ https://www.ncbi.nlm.nih.gov/pubmed/30744595 http://dx.doi.org/10.1186/s12885-019-5353-6 |
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