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Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling

BACKGROUND: Cancer-associated fibroblasts (CAFs), activated by tumour cells, are the predominant type of stromal cells in cancer tissue and play an important role in interacting with neoplastic cells to promote cancer progression. Epithelial-mesenchymal transition (EMT) is a key feature of metastati...

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Detalles Bibliográficos
Autores principales: Goulet, Cassandra Ringuette, Champagne, Audrey, Bernard, Geneviève, Vandal, Dominique, Chabaud, Stéphane, Pouliot, Frédéric, Bolduc, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371428/
https://www.ncbi.nlm.nih.gov/pubmed/30744595
http://dx.doi.org/10.1186/s12885-019-5353-6

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