Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

BACKGROUND: Alternative splicing is a key regulatory mechanism in eukaryotic cells and increases the effective number of functionally distinct gene products. Using bulk RNA sequencing, splicing variation has been studied across human tissues and in genetically diverse populations. This has identifie...

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Detalles Bibliográficos
Autores principales: Linker, Stephanie M., Urban, Lara, Clark, Stephen J., Chhatriwala, Mariya, Amatya, Shradha, McCarthy, Davis J., Ebersberger, Ingo, Vallier, Ludovic, Reik, Wolf, Stegle, Oliver, Bonder, Marc Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371455/
https://www.ncbi.nlm.nih.gov/pubmed/30744673
http://dx.doi.org/10.1186/s13059-019-1644-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371455/
https://www.ncbi.nlm.nih.gov/pubmed/30744673
http://dx.doi.org/10.1186/s13059-019-1644-0

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