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Annexin A1-derived peptide Ac(2-26) in a pilocarpine-induced status epilepticus model: anti-inflammatory and neuroprotective effects
BACKGROUND: The inflammatory process has been described as a crucial mechanism in the pathophysiology of temporal lobe epilepsy. The anti-inflammatory protein annexin A1 (ANXA1) represents an interesting target in the regulation of neuroinflammation through the inhibition of leukocyte transmigration...
Autores principales: | Gimenes, Alexandre D., Andrade, Bruna F. D., Pinotti, José Victor P., Oliani, Sonia M., Galvis-Alonso, Orfa Y., Gil, Cristiane D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371492/ https://www.ncbi.nlm.nih.gov/pubmed/30755225 http://dx.doi.org/10.1186/s12974-019-1414-7 |
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