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The phylogeny of 48 alleles, experimentally verified at 21 kb, and its application to clinical allele detection
BACKGROUND: Sequence information generated from next generation sequencing is often computationally phased using haplotype-phasing algorithms. Utilizing experimentally derived allele or haplotype information improves this prediction, as routinely used in HLA typing. We recently established a large d...
Autores principales: | Srivastava, Kshitij, Wollenberg, Kurt R., Flegel, Willy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371619/ https://www.ncbi.nlm.nih.gov/pubmed/30744658 http://dx.doi.org/10.1186/s12967-019-1791-9 |
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