Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model

BACKGROUND: A structurally diverse group of chemicals, including dioxins [e.g., 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)] and polycyclic aromatic hydrocarbons (PAHs), can xenobiotically activate the aryl hydrocarbon receptor (AHR) and contribute to adverse health effects in humans and wildlife. In...

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Detalles Bibliográficos
Autores principales: Garcia, Gloria R., Shankar, Prarthana, Dunham, Cheryl L., Garcia, Abraham, La Du, Jane K., Truong, Lisa, Tilton, Susan C., Tanguay, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371766/
https://www.ncbi.nlm.nih.gov/pubmed/30398377
http://dx.doi.org/10.1289/EHP3281

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