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Cognitive Enhancer Effects of Low Memantine Doses Are Facilitated by an Alpha7 Nicotinic Acetylcholine Receptor Agonist in Scopolamine-Induced Amnesia in Rats

Alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in learning and memory and are promising targets for pharmacological cognitive enhancement. Memantine, an approved substance for Alzheimer’s disease treatment, is an antagonist of the N-Methyl-D-aspartate receptor (NMDAR) and a...

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Detalles Bibliográficos
Autores principales: Bali, Zsolt Kristóf, Bruszt, Nóra, Tadepalli, Sai Ambika, Csurgyók, Roland, Nagy, Lili Veronika, Tompa, Márton, Hernádi, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371842/
https://www.ncbi.nlm.nih.gov/pubmed/30804787
http://dx.doi.org/10.3389/fphar.2019.00073