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Brigatinib for ALK-positive metastatic non-small-cell lung cancer: design, development and place in therapy

Despite the benefits of first and second generation anaplastic lymphoma kinase (ALK) inhibitors in the management of ALK-rearranged advanced non-small-cell lung cancer (NSCLC), the development of acquired resistance poses an ongoing dilemma. Brigatinib has demonstrated a wider spectrum of preclinica...

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Detalles Bibliográficos
Autores principales:	Ali, Robert, Arshad, Junaid, Palacio, Sofia, Mudad, Raja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372006/ https://www.ncbi.nlm.nih.gov/pubmed/30804663 http://dx.doi.org/10.2147/DDDT.S147499

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