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Anatomy of Mdm2 and Mdm4 in evolution

Mouse double minute (Mdm) genes span an evolutionary timeframe from the ancient eukaryotic placozoa Trichoplax adhaerens to Homo sapiens, implying a significant and possibly conserved cellular role throughout history. Maintenance of DNA integrity and response to DNA damage involve many key regulator...

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Detalles Bibliográficos
Autores principales: Tan, Ban Xiong, Liew, Hoe Peng, Chua, Joy S., Ghadessy, Farid J., Tan, Yaw Sing, Lane, David P., Coffill, Cynthia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372010/
https://www.ncbi.nlm.nih.gov/pubmed/28077607
http://dx.doi.org/10.1093/jmcb/mjx002