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Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt

BACKGROUND: WHO recommends all countries to include a second routine dose of measles containing vaccine (MCV2) in their national routine vaccination schedules regardless of the level of coverage with the first routine dose of measles containing vaccine (MCV1). As of Dec 2016, 26 countries in the Afr...

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Autores principales: Masresha, Balcha G, Luce, Richard, Okeibunor, Joseph, Shibeshi, Messeret Eshetu, Kamadjeu, Raoul, Fall, Amadou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372060/
https://www.ncbi.nlm.nih.gov/pubmed/30766972
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author Masresha, Balcha G
Luce, Richard
Okeibunor, Joseph
Shibeshi, Messeret Eshetu
Kamadjeu, Raoul
Fall, Amadou
author_facet Masresha, Balcha G
Luce, Richard
Okeibunor, Joseph
Shibeshi, Messeret Eshetu
Kamadjeu, Raoul
Fall, Amadou
author_sort Masresha, Balcha G
collection PubMed
description BACKGROUND: WHO recommends all countries to include a second routine dose of measles containing vaccine (MCV2) in their national routine vaccination schedules regardless of the level of coverage with the first routine dose of measles containing vaccine (MCV1). As of Dec 2016, 26 countries in the African Region have introduced MCV2. METHODS: We reviewed the WHO UNICEF coverage estimates for MCV1 and MCV2 in these countries, and the reports of the post introduction evaluation of MCV2 from 11 countries. RESULTS: Twenty three countries have WHO/UNICEF estimates of MCV2 coverage available in 2015. Of these, 2 countries have coverage of ≥ 95% for both MCV1 and MCV2 while 5 countries have coverage of > 80% for both doses. Dropout rates of >20% MCV1 – MCV2 exist in 12 countries. Post-MCV2 introduction evaluations done in 11 countries from 2012 to 2015 showed that inadequate health worker training, insufficient sensitization and awareness generation among parents and suboptimal dose recording practices were common programmatic weaknesses that contributed to the low MCV2 coverage in these countries. CONCLUSION: MCV2 coverage remains low as reflected in large drop-out rates in most countries. Higher MCV2 coverage is necessary to sustainably achieve the regional measles elimination goal. National immunization programs must improve implementation of MCV2 using the standard introduction and evaluation guidelines available for EPI program planning.
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spelling pubmed-63720602019-02-12 Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt Masresha, Balcha G Luce, Richard Okeibunor, Joseph Shibeshi, Messeret Eshetu Kamadjeu, Raoul Fall, Amadou J Immunol Sci Article BACKGROUND: WHO recommends all countries to include a second routine dose of measles containing vaccine (MCV2) in their national routine vaccination schedules regardless of the level of coverage with the first routine dose of measles containing vaccine (MCV1). As of Dec 2016, 26 countries in the African Region have introduced MCV2. METHODS: We reviewed the WHO UNICEF coverage estimates for MCV1 and MCV2 in these countries, and the reports of the post introduction evaluation of MCV2 from 11 countries. RESULTS: Twenty three countries have WHO/UNICEF estimates of MCV2 coverage available in 2015. Of these, 2 countries have coverage of ≥ 95% for both MCV1 and MCV2 while 5 countries have coverage of > 80% for both doses. Dropout rates of >20% MCV1 – MCV2 exist in 12 countries. Post-MCV2 introduction evaluations done in 11 countries from 2012 to 2015 showed that inadequate health worker training, insufficient sensitization and awareness generation among parents and suboptimal dose recording practices were common programmatic weaknesses that contributed to the low MCV2 coverage in these countries. CONCLUSION: MCV2 coverage remains low as reflected in large drop-out rates in most countries. Higher MCV2 coverage is necessary to sustainably achieve the regional measles elimination goal. National immunization programs must improve implementation of MCV2 using the standard introduction and evaluation guidelines available for EPI program planning. 2018-07-28 /pmc/articles/PMC6372060/ /pubmed/30766972 Text en http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Masresha, Balcha G
Luce, Richard
Okeibunor, Joseph
Shibeshi, Messeret Eshetu
Kamadjeu, Raoul
Fall, Amadou
Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title_full Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title_fullStr Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title_full_unstemmed Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title_short Introduction of the Second Dose of Measles Containing Vaccine in the Childhood Vaccination Programs Within the WHO Africa Region – Lessons Learnt
title_sort introduction of the second dose of measles containing vaccine in the childhood vaccination programs within the who africa region – lessons learnt
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372060/
https://www.ncbi.nlm.nih.gov/pubmed/30766972
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