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Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling
The folding of newly synthesized proteins to the native state is a major challenge within the crowded cellular environment, as non-productive interactions can lead to misfolding, aggregation and degradation1. Cells cope with this challenge by coupling synthesis with polypeptide folding and by using...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372068/ https://www.ncbi.nlm.nih.gov/pubmed/30158700 http://dx.doi.org/10.1038/s41586-018-0462-y |