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CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques

Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK) cells, mechanistic data explaining these phenomena are lacking. Following antibody sensitization, NK cells lacking the Fc receptor (FcR) signaling chain (Δg) acquire adaptive features, including robust prolifera...

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Detalles Bibliográficos
Autores principales: Shah, Spandan V., Manickam, Cordelia, Ram, Daniel R., Kroll, Kyle, Itell, Hannah, Permar, Sallie R., Barouch, Dan H., Klatt, Nichole R., Reeves, R. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372106/
https://www.ncbi.nlm.nih.gov/pubmed/30517864
http://dx.doi.org/10.1016/j.celrep.2018.11.020