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CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques
Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK) cells, mechanistic data explaining these phenomena are lacking. Following antibody sensitization, NK cells lacking the Fc receptor (FcR) signaling chain (Δg) acquire adaptive features, including robust prolifera...
Autores principales: | Shah, Spandan V., Manickam, Cordelia, Ram, Daniel R., Kroll, Kyle, Itell, Hannah, Permar, Sallie R., Barouch, Dan H., Klatt, Nichole R., Reeves, R. Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372106/ https://www.ncbi.nlm.nih.gov/pubmed/30517864 http://dx.doi.org/10.1016/j.celrep.2018.11.020 |
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