Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin therapeutics. Here, we show that fish-hunting cone s...

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Detalles Bibliográficos
Autores principales: Ahorukomeye, Peter, Disotuar, Maria M, Gajewiak, Joanna, Karanth, Santhosh, Watkins, Maren, Robinson, Samuel D, Flórez Salcedo, Paula, Smith, Nicholas A, Smith, Brian J, Schlegel, Amnon, Forbes, Briony E, Olivera, Baldomero, Hung-Chieh Chou, Danny, Safavi-Hemami, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372279/
https://www.ncbi.nlm.nih.gov/pubmed/30747102
http://dx.doi.org/10.7554/eLife.41574

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