Successful treatment of severe gastrointestinal manifestations of Henoch–Schonlein Purpura and factor XIII deficiency using cryoprecipitate transfusion

Henoch–Schonlein Purpura (HSP) might present with severe gastrointestinal (GI) involvement. Herein, we report 3 cases of HSP with severe GI manifestations in the form of hematemesis, melena, pancreatitis, and erosive gastritis. Different treatment modalities were not successful. Low factor XIII leve...

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Detalles Bibliográficos
Autores principales: Al Sonbul, Abdullah, Noor, Abdullah, Ahmed, Naser, Al-Mutairi, Norah, Jokhadar, Asma, Al-Marri, Munira, Al-Mayouf, Suliman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372394/
https://www.ncbi.nlm.nih.gov/pubmed/30805443
http://dx.doi.org/10.1016/j.ijpam.2015.06.003
Descripción
Sumario:Henoch–Schonlein Purpura (HSP) might present with severe gastrointestinal (GI) involvement. Herein, we report 3 cases of HSP with severe GI manifestations in the form of hematemesis, melena, pancreatitis, and erosive gastritis. Different treatment modalities were not successful. Low factor XIII levels were found in all patients and Cryoprecipitate transfusion resulted in significant immediate clinical improvement.

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