Hsp90ab1 stabilizes LRP5 to promote epithelial–mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression

Hsp90ab1 is upregulated in numerous solid tumors, which is thought to induce the angiogenesis and promote cancer metastasis. However, it’s actions in gastric cancer (GC) has not been exhibited. In this study, Hsp90ab1 was demonstrated to be overexpressed and correlated with the poor prognosis, proli...

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Detalles Bibliográficos
Autores principales: Wang, Huanan, Deng, Guangxu, Ai, Meiling, Xu, Zhijun, Mou, Tingyu, Yu, Jiang, Liu, Hao, Wang, Shuang, Li, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372478/
https://www.ncbi.nlm.nih.gov/pubmed/30305727
http://dx.doi.org/10.1038/s41388-018-0532-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372478/
https://www.ncbi.nlm.nih.gov/pubmed/30305727
http://dx.doi.org/10.1038/s41388-018-0532-5

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