Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence

Liquid biopsies (circulating tumor DNA—ctDNA testing) are increasingly being utilized in clinical trials as well as practice for the detection of cancer, monitoring of tumor genomic abnormalities, response to treatment and early detection of relapse/recurrence. Here, we present a challenging case wh...

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Detalles Bibliográficos
Autores principales: Soyano, Aixa E., Baldeo, Candice, Kasi, Pashtoon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372543/
https://www.ncbi.nlm.nih.gov/pubmed/30788289
http://dx.doi.org/10.3389/fonc.2019.00046
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author Soyano, Aixa E.
Baldeo, Candice
Kasi, Pashtoon M.
author_facet Soyano, Aixa E.
Baldeo, Candice
Kasi, Pashtoon M.
author_sort Soyano, Aixa E.
collection PubMed
description Liquid biopsies (circulating tumor DNA—ctDNA testing) are increasingly being utilized in clinical trials as well as practice for the detection of cancer, monitoring of tumor genomic abnormalities, response to treatment and early detection of relapse/recurrence. Here, we present a challenging case where liquid biopsy was used to confirm an early recurrence of pancreatic cancer where acquisition of tissue was not safe or feasible on more than one occasion.
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spelling pubmed-63725432019-02-20 Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence Soyano, Aixa E. Baldeo, Candice Kasi, Pashtoon M. Front Oncol Oncology Liquid biopsies (circulating tumor DNA—ctDNA testing) are increasingly being utilized in clinical trials as well as practice for the detection of cancer, monitoring of tumor genomic abnormalities, response to treatment and early detection of relapse/recurrence. Here, we present a challenging case where liquid biopsy was used to confirm an early recurrence of pancreatic cancer where acquisition of tissue was not safe or feasible on more than one occasion. Frontiers Media S.A. 2019-02-06 /pmc/articles/PMC6372543/ /pubmed/30788289 http://dx.doi.org/10.3389/fonc.2019.00046 Text en Copyright © 2019 Soyano, Baldeo and Kasi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Soyano, Aixa E.
Baldeo, Candice
Kasi, Pashtoon M.
Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title_full Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title_fullStr Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title_full_unstemmed Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title_short Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence
title_sort adjunctive use of circulating tumor dna testing in detecting pancreas cancer recurrence
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372543/
https://www.ncbi.nlm.nih.gov/pubmed/30788289
http://dx.doi.org/10.3389/fonc.2019.00046
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