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Immunoglobulin G modulation of the melanocortin 4 receptor signaling in obesity and eating disorders

Melanocortin 4 receptor (MC4R) plays a key role in regulation of appetite activated by its main ligand α-melanocyte-stimulating hormone (α-MSH) in both central and peripheral targets. α-MSH also binds to circulating immunoglobulins (Igs) but the functional significance of such immune complexes (ICs)...

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Detalles Bibliográficos
Autores principales:	Lucas, Nicolas, Legrand, Romain, Bôle-Feysot, Christine, Breton, Jonathan, Coëffier, Moïse, Akkermann, Kirsti, Järv, Anu, Harro, Jaanus, Déchelotte, Pierre, Fetissov, Sergueï O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372612/ https://www.ncbi.nlm.nih.gov/pubmed/30755592 http://dx.doi.org/10.1038/s41398-019-0422-9

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