Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components

Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. We have extended factor analysis and developed a novel profile data analysis method: orthogonal linear sepa...

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Detalles Bibliográficos
Autores principales: Mizuno, Tadahaya, Kinoshita, Setsuo, Ito, Takuya, Maedera, Shotaro, Kusuhara, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372619/
https://www.ncbi.nlm.nih.gov/pubmed/30755704
http://dx.doi.org/10.1038/s41598-019-38528-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372619/
https://www.ncbi.nlm.nih.gov/pubmed/30755704
http://dx.doi.org/10.1038/s41598-019-38528-4

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