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Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components
Drugs have multiple, not single, effects. Decomposition of drug effects into basic components helps us to understand the pharmacological properties of a drug and contributes to drug discovery. We have extended factor analysis and developed a novel profile data analysis method: orthogonal linear sepa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372619/ https://www.ncbi.nlm.nih.gov/pubmed/30755704 http://dx.doi.org/10.1038/s41598-019-38528-4 |