DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress

The unfolded protein response (UPR) triggered by endoplasmic reticulum (ER) stress is a feature of many neurodegenerative diseases including Alzheimer’s disease, Huntington’s disease and Parkinson’s disease (PD). Although the vast majority of PD is sporadic, mutations in a number of genes including...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jungwoo, Kim, Kwang Soo, Iyirhiaro, Grace O., Marcogliese, Paul C., Callaghan, Steve M., Qu, Dianbo, Kim, Woo Jae, Slack, Ruth S., Park, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372623/
https://www.ncbi.nlm.nih.gov/pubmed/30755590
http://dx.doi.org/10.1038/s41419-019-1354-2

Ejemplares similares

Ejemplares similares