Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer

Bladder cancer is one of the most common and highly vascularized cancers. To better understand its genomic structure and underlying etiology, we conduct whole-genome and targeted sequencing in urothelial bladder carcinomas (UBCs, the most common type of bladder cancer). Recurrent mutations in noncod...

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Detalles Bibliográficos
Autores principales: Wu, Song, Ou, Tong, Xing, Nianzeng, Lu, Jiang, Wan, Shengqing, Wang, Changxi, Zhang, Xi, Yang, Feiya, Huang, Yi, Cai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372626/
https://www.ncbi.nlm.nih.gov/pubmed/30755618
http://dx.doi.org/10.1038/s41467-019-08576-5

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