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PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma
Serine proteases have been implicated as key drivers and facilitators of lung cancer malignancy, and while these proteins represent straightforward targets for therapeutic inhibitors, identification of optimal points for intervention has been complicated by the complex networks in which these enzyme...
Autores principales: | Ma, Honghai, Hockla, Alexandra, Mehner, Christine, Coban, Matt, Papo, Niv, Radisky, Derek C., Radisky, Evette S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372636/ https://www.ncbi.nlm.nih.gov/pubmed/30755669 http://dx.doi.org/10.1038/s41598-018-38362-0 |
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