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Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein
Biological characterisation of membrane proteins lags behind that of soluble proteins. This reflects issues with the traditional use of detergents for extraction, as the surrounding lipids are generally lost, with adverse structural and functional consequences. In contrast, styrene maleic acid (SMA)...
Autores principales: | Teo, Alvin C. K., Lee, Sarah C., Pollock, Naomi L., Stroud, Zoe, Hall, Stephen, Thakker, Alpesh, Pitt, Andrew R., Dafforn, Timothy R., Spickett, Corinne M., Roper, David I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372662/ https://www.ncbi.nlm.nih.gov/pubmed/30755655 http://dx.doi.org/10.1038/s41598-018-37962-0 |
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