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A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae

In eukaryotes, telomeres determine cell proliferation potential by triggering replicative senescence in the absence of telomerase. In Saccharomyces cerevisiae, senescence is mainly dictated by the first telomere that reaches a critically short length, activating a DNA-damage-like response. How the c...

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Detalles Bibliográficos
Autores principales:	Jolivet, Pascale, Serhal, Kamar, Graf, Marco, Eberhard, Stephan, Xu, Zhou, Luke, Brian, Teixeira, Maria Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372760/ https://www.ncbi.nlm.nih.gov/pubmed/30755624 http://dx.doi.org/10.1038/s41598-018-38000-9

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