Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes

Metabolic syndrome is characterized by disturbances in glucose homeostasis and the development of low-grade systemic inflammation, which increase the risk to develop type 2 diabetes mellitus (T2DM). Type-2 innate lymphoid cells (ILC2s) are a recently discovered immune population secreting Th2 cytoki...

Descripción completa

Detalles Bibliográficos
Autores principales: Galle-Treger, Lauriane, Sankaranarayanan, Ishwarya, Hurrell, Benjamin P., Howard, Emily, Lo, Richard, Maazi, Hadi, Lewis, Gavin, Banie, Homayon, Epstein, Alan L., Hu, Peisheng, Rehan, Virender K., Gilliland, Frank D., Allayee, Hooman, Soroosh, Pejman, Sharpe, Arlene H., Akbari, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372786/
https://www.ncbi.nlm.nih.gov/pubmed/30755607
http://dx.doi.org/10.1038/s41467-019-08449-x

Ejemplares similares

Ejemplares similares