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OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates

During somatic cell reprogramming to induced pluripotent stem cells (iPSCs), fibroblasts undergo dynamic molecular changes, including a mesenchymal-to-epithelial transition (MET) and gain of pluripotency; processes that are influenced by Yamanaka factor stoichiometry. For example, in early reprogram...

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Detalles Bibliográficos
Autores principales: Kagawa, Harunobu, Shimamoto, Ren, Kim, Shin-Il, Oceguera-Yanez, Fabian, Yamamoto, Takuya, Schroeder, Timm, Woltjen, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372973/
https://www.ncbi.nlm.nih.gov/pubmed/30639212
http://dx.doi.org/10.1016/j.stemcr.2018.12.008