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Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections
[Image: see text] DNA-encoded chemical libraries (DELs) provide a high-throughput and cost-effective route for screening billions of unique molecules for binding affinity for diverse protein targets. Identifying candidate compounds from these libraries involves affinity selection, DNA sequencing, an...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372980/ https://www.ncbi.nlm.nih.gov/pubmed/30672692 http://dx.doi.org/10.1021/acscombsci.8b00116 |