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Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital

OBJECTIVE: The aim was to establish the reliability of the SWRD score as a predictor of both renal and bladder outcomes in posterior urethral valves. This retrospective study included 67 patients with PUVs at King Abdul-Aziz University Hospital. The score was calculated from voiding cystourethrogram...

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Autores principales: Neyas, Afnan, Bajaba, Rana, AlThomali, Rahaf, Alturkistani, Rahaf, AlSawaf, Baraah, Alrefai, Weaam, Hefni, Lujain, Aldoobie, Lamees, Desoky, Sherif, Kari, Jameela, Safdar, Osama Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373006/
https://www.ncbi.nlm.nih.gov/pubmed/30755266
http://dx.doi.org/10.1186/s13104-019-4120-8
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author Neyas, Afnan
Bajaba, Rana
AlThomali, Rahaf
Alturkistani, Rahaf
AlSawaf, Baraah
Alrefai, Weaam
Hefni, Lujain
Aldoobie, Lamees
Desoky, Sherif
Kari, Jameela
Safdar, Osama Y.
author_facet Neyas, Afnan
Bajaba, Rana
AlThomali, Rahaf
Alturkistani, Rahaf
AlSawaf, Baraah
Alrefai, Weaam
Hefni, Lujain
Aldoobie, Lamees
Desoky, Sherif
Kari, Jameela
Safdar, Osama Y.
author_sort Neyas, Afnan
collection PubMed
description OBJECTIVE: The aim was to establish the reliability of the SWRD score as a predictor of both renal and bladder outcomes in posterior urethral valves. This retrospective study included 67 patients with PUVs at King Abdul-Aziz University Hospital. The score was calculated from voiding cystourethrogram before and after the relief of obstruction, and estimated glomerular filtration rates (eGFRs) were calculated as well. RESULTS: Based on Spearman correlations, both baseline eGFRs and SWRD scores can be possible predictors of long-term renal outcomes, as a significant positive correlation between the baseline eGFRs and the last eGFRs was found (p = 0.005). A significant negative correlation was also found between the SWRD score calculated before the intervention and the last eGFRs (p = 0.02). Additionally, the baseline SWRD scores can be possible predictors of short-term bladder outcomes, as the correlation analysis showed a positive relationship between the baseline SWRD scores and the SWRD scores calculated within 2 months after the intervention (p < 0.0001). A significant decrease in SWRD scores and eGFRs was found from before to after the intervention, regardless of the type of intervention. In conclusion, the SWRD scoring system proved to be a potentially promising tool in the anticipation of the clinical outcomes of PUVs.
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spelling pubmed-63730062019-02-25 Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital Neyas, Afnan Bajaba, Rana AlThomali, Rahaf Alturkistani, Rahaf AlSawaf, Baraah Alrefai, Weaam Hefni, Lujain Aldoobie, Lamees Desoky, Sherif Kari, Jameela Safdar, Osama Y. BMC Res Notes Research Note OBJECTIVE: The aim was to establish the reliability of the SWRD score as a predictor of both renal and bladder outcomes in posterior urethral valves. This retrospective study included 67 patients with PUVs at King Abdul-Aziz University Hospital. The score was calculated from voiding cystourethrogram before and after the relief of obstruction, and estimated glomerular filtration rates (eGFRs) were calculated as well. RESULTS: Based on Spearman correlations, both baseline eGFRs and SWRD scores can be possible predictors of long-term renal outcomes, as a significant positive correlation between the baseline eGFRs and the last eGFRs was found (p = 0.005). A significant negative correlation was also found between the SWRD score calculated before the intervention and the last eGFRs (p = 0.02). Additionally, the baseline SWRD scores can be possible predictors of short-term bladder outcomes, as the correlation analysis showed a positive relationship between the baseline SWRD scores and the SWRD scores calculated within 2 months after the intervention (p < 0.0001). A significant decrease in SWRD scores and eGFRs was found from before to after the intervention, regardless of the type of intervention. In conclusion, the SWRD scoring system proved to be a potentially promising tool in the anticipation of the clinical outcomes of PUVs. BioMed Central 2019-02-12 /pmc/articles/PMC6373006/ /pubmed/30755266 http://dx.doi.org/10.1186/s13104-019-4120-8 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Neyas, Afnan
Bajaba, Rana
AlThomali, Rahaf
Alturkistani, Rahaf
AlSawaf, Baraah
Alrefai, Weaam
Hefni, Lujain
Aldoobie, Lamees
Desoky, Sherif
Kari, Jameela
Safdar, Osama Y.
Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title_full Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title_fullStr Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title_full_unstemmed Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title_short Correlation between the estimated GFR and SWRD score in patients with posterior urethral valves at King Abdul-Aziz University Hospital
title_sort correlation between the estimated gfr and swrd score in patients with posterior urethral valves at king abdul-aziz university hospital
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373006/
https://www.ncbi.nlm.nih.gov/pubmed/30755266
http://dx.doi.org/10.1186/s13104-019-4120-8
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