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Re: “Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community” (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

A recent publication by Lim et al. 2018 (Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community) strongly concluded that the microbiome of amniotic fluid primarily originates from reagent contamination. However, upon closer inspection of the methods used and da...

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Detalles Bibliográficos
Autores principales: Payne, M. S., Keelan, J. A., Stinson, L. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373022/
https://www.ncbi.nlm.nih.gov/pubmed/30755258
http://dx.doi.org/10.1186/s40168-019-0642-5
Descripción
Sumario:A recent publication by Lim et al. 2018 (Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community) strongly concluded that the microbiome of amniotic fluid primarily originates from reagent contamination. However, upon closer inspection of the methods used and data presented in this study, in particular the supplementary data, such conclusions do not appear to be supported by the results. We outline such methodological/data interpretation concerns and invite the authors to discuss these.