Cargando…
Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study
BACKGROUND: The rising incidence of metabolic syndrome (MetS) is a major public health problem. The inflammatory potential of diet contributes to the development of MetS. The aim of this study was to investigate the relationship between empirical dietary inflammatory pattern (EDIP) and risk of MetS...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373046/ https://www.ncbi.nlm.nih.gov/pubmed/30805034 http://dx.doi.org/10.1186/s13098-019-0411-4 |
_version_ | 1783394890732797952 |
---|---|
author | Shakeri, Zeinab Mirmiran, Parvin Khalili-Moghadam, Sajjad Hosseini-Esfahani, Firoozeh Ataie-Jafari, Asal Azizi, Fereidoun |
author_facet | Shakeri, Zeinab Mirmiran, Parvin Khalili-Moghadam, Sajjad Hosseini-Esfahani, Firoozeh Ataie-Jafari, Asal Azizi, Fereidoun |
author_sort | Shakeri, Zeinab |
collection | PubMed |
description | BACKGROUND: The rising incidence of metabolic syndrome (MetS) is a major public health problem. The inflammatory potential of diet contributes to the development of MetS. The aim of this study was to investigate the relationship between empirical dietary inflammatory pattern (EDIP) and risk of MetS among the Tehranian population. Our hypothesis was that high EDIP would increase the risk of MetS and its components. METHODS: In this prospective study, 2216 adults were selected from among the Tehran Lipid and Glucose Study participants. The usual dietary intakes were estimated using a valid and reliable food frequency questionnaire. Biochemical and anthropometric measurements were assessed at baseline and over 6.2 years of follow up. MetS components were defined according to the modified national Cholesterol Education Program Adult Treatment Panel III. The inflammatory potential of diet was calculated using EDIP score; more positive scores means higher pro-inflammatory diet. Adjusted logistic regression models were used to estimate the occurrence of MetS and its components across quartiles of EDIP score. RESULTS: Mean ± SD for EDIP score was 0.61 ± 0.40 (range − 2.3 to 6.9). Participants with the highest EDIP scores, had a higher risk of MetS incidence compared to those with the lowest score (OR: 1.75, 95% CI 1.21–2.54, P(trend) = 0.003). Among the MetS components, hyperglycemia, abdominal obesity, and low HDL-C had a significant positive association with EDIP score; (OR: 1.46, 95% CI 1.03–2.08, P(trend) = 0.026), (OR: 1.43, 95% CI 1.03–1.97, P(trend) = 0.046), and (OR: 1.57, 95% CI 1.34–2.19, P(trend) = 0.015), respectively. No significant association was found between EDIP score, hypertension and hypertriglyceridemia. CONCLUSION: Our finding indicated that higher intake of the pro-inflammatory diet may be an independent risk factor for the development of MetS, hyperglycemia, low HDL-C and abdominal obesity in Tehranian adults. |
format | Online Article Text |
id | pubmed-6373046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-63730462019-02-25 Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study Shakeri, Zeinab Mirmiran, Parvin Khalili-Moghadam, Sajjad Hosseini-Esfahani, Firoozeh Ataie-Jafari, Asal Azizi, Fereidoun Diabetol Metab Syndr Research BACKGROUND: The rising incidence of metabolic syndrome (MetS) is a major public health problem. The inflammatory potential of diet contributes to the development of MetS. The aim of this study was to investigate the relationship between empirical dietary inflammatory pattern (EDIP) and risk of MetS among the Tehranian population. Our hypothesis was that high EDIP would increase the risk of MetS and its components. METHODS: In this prospective study, 2216 adults were selected from among the Tehran Lipid and Glucose Study participants. The usual dietary intakes were estimated using a valid and reliable food frequency questionnaire. Biochemical and anthropometric measurements were assessed at baseline and over 6.2 years of follow up. MetS components were defined according to the modified national Cholesterol Education Program Adult Treatment Panel III. The inflammatory potential of diet was calculated using EDIP score; more positive scores means higher pro-inflammatory diet. Adjusted logistic regression models were used to estimate the occurrence of MetS and its components across quartiles of EDIP score. RESULTS: Mean ± SD for EDIP score was 0.61 ± 0.40 (range − 2.3 to 6.9). Participants with the highest EDIP scores, had a higher risk of MetS incidence compared to those with the lowest score (OR: 1.75, 95% CI 1.21–2.54, P(trend) = 0.003). Among the MetS components, hyperglycemia, abdominal obesity, and low HDL-C had a significant positive association with EDIP score; (OR: 1.46, 95% CI 1.03–2.08, P(trend) = 0.026), (OR: 1.43, 95% CI 1.03–1.97, P(trend) = 0.046), and (OR: 1.57, 95% CI 1.34–2.19, P(trend) = 0.015), respectively. No significant association was found between EDIP score, hypertension and hypertriglyceridemia. CONCLUSION: Our finding indicated that higher intake of the pro-inflammatory diet may be an independent risk factor for the development of MetS, hyperglycemia, low HDL-C and abdominal obesity in Tehranian adults. BioMed Central 2019-02-12 /pmc/articles/PMC6373046/ /pubmed/30805034 http://dx.doi.org/10.1186/s13098-019-0411-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Shakeri, Zeinab Mirmiran, Parvin Khalili-Moghadam, Sajjad Hosseini-Esfahani, Firoozeh Ataie-Jafari, Asal Azizi, Fereidoun Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title | Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title_full | Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title_fullStr | Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title_full_unstemmed | Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title_short | Empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: Tehran Lipid and Glucose Study |
title_sort | empirical dietary inflammatory pattern and risk of metabolic syndrome and its components: tehran lipid and glucose study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373046/ https://www.ncbi.nlm.nih.gov/pubmed/30805034 http://dx.doi.org/10.1186/s13098-019-0411-4 |
work_keys_str_mv | AT shakerizeinab empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy AT mirmiranparvin empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy AT khalilimoghadamsajjad empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy AT hosseiniesfahanifiroozeh empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy AT ataiejafariasal empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy AT azizifereidoun empiricaldietaryinflammatorypatternandriskofmetabolicsyndromeanditscomponentstehranlipidandglucosestudy |