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Cornification of nail keratinocytes requires autophagy for bulk degradation of intracellular proteins while sparing components of the cytoskeleton
Epidermal keratinocytes undergo cornification to form the cellular building blocks of hard skin appendages such as nails and the protective layer on the surface of the skin. Cornification requires the cross-linking of structural proteins and the removal of other cellular components to form mechanica...
Autores principales: | Jaeger, Karin, Sukseree, Supawadee, Zhong, Shaomin, Phinney, Brett S., Mlitz, Veronika, Buchberger, Maria, Narzt, Marie Sophie, Gruber, Florian, Tschachler, Erwin, Rice, Robert H., Eckhart, Leopold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373260/ https://www.ncbi.nlm.nih.gov/pubmed/30552537 http://dx.doi.org/10.1007/s10495-018-1505-4 |
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