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Bacterial supernatants elevate glucose-dependent insulin secretion in rat pancreatic INS-1 line and islet β-cells via PI3K/AKT signaling

Diabetes and periodontitis are considered associated chronic diseases, and hyperinsulinemia in prediabetes has been shown to be present in normoglycemic animals with periodontitis. As periodontal bacterial species are significant sources of endotoxemia and may directly stimulate insulin secretion, w...

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Detalles Bibliográficos
Autores principales: Ramenzoni, Liza L., Zuellig, Richard A., Hussain, Abbas, Lehmann, Roger, Heumann, Christian, Attin, Thomas, Schmidlin, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373304/
https://www.ncbi.nlm.nih.gov/pubmed/30039349
http://dx.doi.org/10.1007/s11010-018-3408-7