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Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation

Kappa receptor activation by dynorphins contributes to the anxiogenic, dysphoric, and cognitive disrupting effects of repeated stress, suggesting that kappa receptor antagonists might have therapeutic utility in the treatment of stress disorders. Three classes of kappa antagonists have been distingu...

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Detalles Bibliográficos
Autores principales:	Chavkin, Charles, Cohen, Joshua H., Land, Benjamin B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373456/ https://www.ncbi.nlm.nih.gov/pubmed/30787880 http://dx.doi.org/10.3389/fphar.2019.00088

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