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Human Pluripotent Stem Cell-Derived Striatal Interneurons: Differentiation and Maturation In Vitro and in the Rat Brain

Striatal interneurons are born in the medial and caudal ganglionic eminences (MGE and CGE) and play an important role in human striatal function and dysfunction in Huntington's disease and dystonia. MGE/CGE-like neural progenitors have been generated from human pluripotent stem cells (hPSCs) fo...

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Detalles Bibliográficos
Autores principales: Noakes, Zoe, Keefe, Francesca, Tamburini, Claudia, Kelly, Claire M., Cruz Santos, Maria, Dunnett, Stephen B., Errington, Adam C., Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373547/
https://www.ncbi.nlm.nih.gov/pubmed/30661995
http://dx.doi.org/10.1016/j.stemcr.2018.12.014