Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction

The human colonic mucosa contains regulatory type 1-like (Tr1-like, i.e., IL-10-secreting and Foxp3-negative) T cells specific for the gut Clostridium Faecalibacterium prausnitzii (F. prausnitzii), which are both decreased in Crohn's disease patients. These data, together with the demonstration...

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Detalles Bibliográficos
Autores principales: Alameddine, Joudy, Godefroy, Emmanuelle, Papargyris, Loukas, Sarrabayrouse, Guillaume, Tabiasco, Julie, Bridonneau, Chantal, Yazdanbakhsh, Karina, Sokol, Harry, Altare, Frédéric, Jotereau, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373781/
https://www.ncbi.nlm.nih.gov/pubmed/30787928
http://dx.doi.org/10.3389/fimmu.2019.00143

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