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Low Incidence of the DPD IVS14+1G>A Polymorphism in Jordanian Breast and Colorectal Cancer patients

BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) is a crucial enzyme in the catabolism of 5-fluorouracil (5-FU), a drug that is frequently used in cancer therapy. Patients with deficient DPD activity are at risk of developing severe 5-FU–associated toxicity. One possible cause of deficiency is gene...

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Detalles Bibliográficos
Autores principales:	Al-Khateeb, Mohammad, Awidi, Abdalla, Al-Hadidi, Kamal, Battah, Abdelkader
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373818/ https://www.ncbi.nlm.nih.gov/pubmed/28670884 http://dx.doi.org/10.22034/APJCP.2017.18.6.1651

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